SLC Webinar Invitation: Polypharmacy and the Challenges of Optimizing Pharmacotherapy in Complex Patients

SPS is pleased to announce the following webinar hosted by the Scientific Liaison Coalition: 

Polypharmacy and the Challenges of Optimizing Pharmacotherapy in Complex Patients
Tuesday, February 28, 2017, 11:00 AM–12:30 PM ET USA

Presented by Cathy Yeung, Pharm D, PhD, MPH; Assistant Professor, Department of Pharmacy, University of Washington School of Pharmacy, Seattle, Washington.


One of the greatest challenges facing clinical pharmacists is the rapid growth of polypharmacy, in which patients are prescribed 10 or more medications, and the associated increased risks of adverse drug reactions, drug-drug interactions, and drug-disease interactions. Selection of drugs, doses, and timing of doses is particularly difficult in patients who are elderly or have accompanying organ impairment (liver, kidney). Drug pharmacokinetics in the setting of polypharmacy and organ impairment is complicated by overlapping clearance modalities, including drug metabolizing enzymes and drug transporters. In this webinar, we will review major pathways of drug metabolism and identify clinically relevant drug transporters. The impact of renal impairment on non-renal drug clearance will be discussed. Finally, a clinically relevant drug metabolism/drug transporter/food interaction will be presented.

Dr. Yeung’s training encompasses clinical pharmacy, medicinal chemistry, pharmacokinetics, and epidemiology. Her research focuses on optimizing pharmacotherapy in patients with chronic kidney disease using molecular tools to probe proximal tubule transport, mathematical modeling of substrate transit in the proximal tubule, innovative 3-dimensional microfluidic models, and clinical pharmacokinetics studies. 

The mission of the SLC is “improving the ability of societies to partner with other domestic and international organizations that have objectives consistent with the goal of increasing the impact of the science of toxicology to improve public health" by:

  • Strengthening partnerships among scientific- and health-based organizations to increase awareness of the impact of toxicology and related subjects on human health, and
  • Functioning as a means to enhance cooperation among societies as equals with the goal of accomplishing tasks benefiting human health and disease prevention through joint and shared activities. 

This webinar is open only to members of the partnering societies of the SLC, which are listed on the SLC website and you must register to attend. For more information on the SLC, please contact Marcia Lawson.


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